Fibromyalgia: Pathophysiology and new developments of treatment Fibromiyalji: Patofizyoloji ve tedavideki yeni gelişmeler
Journal of Rheumatology and Medical Rehabilitation, cilt.22, sa.4, ss.88-94, 2011 (Scopus)
- Yayın Türü: Makale / Derleme
- Cilt numarası: 22 Sayı: 4
- Basım Tarihi: 2011
- Dergi Adı: Journal of Rheumatology and Medical Rehabilitation
- Derginin Tarandığı İndeksler: Scopus
- Sayfa Sayıları: ss.88-94
- Anahtar Kelimeler: Fibromyalgia, Pathophysiology, Treatment
- Kırklareli Üniversitesi Adresli: Hayır
Özet
Fibromyalgia is a divisive disease and marked by fatigue, sleep disorders, cognitive dysfunction and depressed mood. It is a one of chronic widespread pain syndromes. There is no spesific laboratory tests, radyological finding or imaging methods. The pathophysiology of fibromyalgia, involves neuroendocrine system, autonomic nervous system anomalies, genetic factors, psychosocial changes and environmental stress factors. Also these factors are reason of recurren or persistent pain, emotional stress,irritable bowel syndrome (IBS) ve temperomandibular disorder (TMD) and major affective or anxiety disorders. There is four important treatment strategy for fibromyalgia. These are: decreasing periferic pain specially at muscles, leading central sensitization, sleep disorders and negative affect conditon such as depression. There is evidence indicating that determination of a multi-faceted program for the treatment of fibromyalgia as education, medical treatment, exercise and cognitive-behavioral therapy (CBT). In this review the pathophysiology and treatment of fibromyalgia is reevaluated by new developments. Copyright © 2011 by Türk Tibbi Rehabilitasyon Kurumu Derneǧi.