Synthesis of isoxazolopyridines and spirooxindoles under ultrasonic irradiation and evaluation of their antioxidant activity


PELİT E.

Journal of Chemistry, cilt.2017, 2017 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 2017
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1155/2017/9161505
  • Dergi Adı: Journal of Chemistry
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Kırklareli Üniversitesi Adresli: Evet

Özet

New polycyclic-fused isoxazolo[4,5-e]pyridines and spirooxindoles were obtained via multicomponent reaction of 5-amino-3-methylisoxazole, indan-1,3-dione, and aromatic aldehydes and reaction of 5-amino-3-methylisoxazole, isatin, and β-diketones in the presence of (±)-camphor-10-sulfonic acid as an effective and nontoxic organocatalyst under ultrasound-promoted conditions. The antioxidant activity of the novel synthesized compounds was studied.