Factors associated with pulmonary recurrence after pulmonary metastasectomy for sarcomatous disease


Tanju S., SARIÇAM M., Kaba E., Kapdagli M., Dilege S., Toker A.

Surgery Today, cilt.44, sa.5, ss.914-918, 2014 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 44 Sayı: 5
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1007/s00595-013-0796-x
  • Dergi Adı: Surgery Today
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.914-918
  • Anahtar Kelimeler: Metastasectomy, Sarcoma, Recurrence
  • Kırklareli Üniversitesi Adresli: Evet

Özet

Purpose: To analyze the factors associated with survival and pulmonary recurrence after complete metastasectomy for patients with sarcomatous disease. Methods: Among the 51 patients who underwent complete pulmonary metastasectomy at our hospital between January 2002 and November 2010, 30 (58.8 %) suffered pulmonary recurrence in an ipsilateral hemithorax. We analyzed the factors affecting survival and recurrence after complete metastasectomy. Results: The 51 patients who underwent pulmonary metastasectomy comprised 33 male and 18 female patients, with a median age of 22 years (range 11-61 years). The median survival was 24 months. Multivariate analysis revealed recurrence (p = 0.016) and the type of tumor (p = 0.024) as independent predictors of survival. Recurrence developed in 30 (58.8 %) patients. The risk of recurrence was higher in patients with a DFI <12 months and >1 metastasis resected during the initial metastasectomy. Conclusions: Based on the findings of our analysis, patients with a DFI <12 months and >1 metastases resected during initial surgery have a higher risk of recurrence. We recommend postoperative follow-up at frequent intervals and reconsideration of oncological treatment after complete resection. © 2013 Springer.