Synthesis of novel Schiff bases and azol-β-lactam derivatives starting from morpholine and thiomorpholine and investigation of their antitubercular, antiurease activity, acethylcolinesterase inhibition effect and antioxidant capacity
Bioorganic Chemistry, cilt.88, 2019 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 88
- Basım Tarihi: 2019
- Doi Numarası: 10.1016/j.bioorg.2019.102928
- Dergi Adı: Bioorganic Chemistry
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Anahtar Kelimeler: Schiff base, beta-Lactam, Morpholine, Thiomorpholine, Azole, Antitubercular activity, Antiurease activity, Acethylcolinesterase, Antioxidant
- Kırklareli Üniversitesi Adresli: Evet
Özet
In this study, new Schiff bases and β-lactam derivatives containing morpholine and thio morpholine nuclei were synthesized. Antimicrobial, antioxidant, antimicrobial and antioxidant properties of all synthesized compounds were investigated and highly effective products were obtained. In this context, new effective structures were introduced to the literature.